Pope Francis lives his Petrine ministry as close as possible to the faithful. This becomes evident in a special way when it comes to all those who are marginalized for various reasons. Among them, occupying a special place in the preaching of the Pontiff from Argentina, are sick people. As such, we have gathered here the most significant words addressed to them by Francis. It is a collection of precious reflections, thoughts and prayers taken from his speeches, messages, homilies, and Angelus addresses over a span of more than four years, that is to say, from the beginning of his election to the See of Peter until June of 2017. Worthy of great interest are these words of the Pope which, thanks to his spontaneity, his attention towards the weakest, and to his simple but credible language, manage to break through the hearts of people and act effectively as a balm and a sign of hope, opening the hearts of its readers to the fervent love of God the Father.